User:Edit guy42/Alcoholic liver disease
Although in rare cases liver cirrhosis is reversible, the disease process remains mostly irreversible. Liver transplantation remains the only definitive therapy. Today, survival after liver transplantation is similar for people with ALD and non-ALD. The requirements for transplant listing vary among transplant centers. A period of alcohol abstinence for at least 6 months is often used prior to liver transplant. Sustained sobriety may improve liver function enough to avoid transplantation and allows clinicians to assess patient adherence to treatment, however there is neither a consensus nor absolute requirement on timing. [1] Additionally the duration of abstinence prior to transplantation has not been proven to be related to the risk of recidivism. This suggests the risk of relapse may be more related to psychosocial factors which can be carefully evaluated before transplantation by a team of mental health providers and social workers. [2]Relapse to alcohol use after transplant listing results in delisting. Re-listing is possible in many institutions, but only after 3–6 months of sobriety. There are limited data on transplant survival in patients transplanted for acute alcoholic hepatitis, but it is believed to be similar to that in nonacute ALD, non-ALD, and alcoholic hepatitis with MDF less than 32.
- ^ "EASL Clinical Practice Guidelines: Liver transplantation". Journal of Hepatology. 64 (2): 433–485. 2016-02. doi:10.1016/j.jhep.2015.10.006.
{{cite journal}}: Check date values in:|date=(help) - ^ Bertha, Madeline; Choi, Gina; Mellinger, Jessica (2021-06). "Diagnosis and Treatment of Alcohol‐Associated Liver Disease: A Patient‐Friendly Summary of the 2019 AASLD Guidelines". Clinical Liver Disease. 17 (6): 418–423. doi:10.1002/cld.1129. ISSN 2046-2484. PMC 8340354. PMID 34386207.
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