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Shalini Prasad

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Shalini Prasad is an India-born biological engineer, Cecil H. and Ida Green Professor of Systems Biology Science, and head of the Bioengineering Department at The University of Texas at Dallas. She was elected to the American Institute for Medical and Biological Engineering College of Fellows in February 2022 "for pioneering contributions in engineering sweat wearables for disease tracking and management for chronic diseases and prognostic monitoring in pandemics."[1] Shalini Prasad has held faculty positions at several universities and is a co-founder of a technology company called EnLiSense LLC.

Biography

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At the University of Madras, India, Shalini Prasad obtained her bachelor's degree of Electronics and Communications Engineering. She then obtained her Ph.D. in Electrical Engineering at the University of California, Riverside.[2]

Career

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She was an assistant professor at Portland State University from January 2005 to August 2008 and at Arizona State University from August 2008 to August 2010. She served as an associate professor at Wichita State University from August 2010 to August 2011. She currently works at the University of Texas, Dallas as a professor and has worked there since August 2011.[3]

Shalini Prasad has published articles about her research in the National Library of Medicine. Some of her work includes detecting THC from saliva, being able to monitor patients with brain injuries, and being able to determine blood alcohol levels through sweat. Some of her more recent articles from 2023 consist of the development of a wearable device to monitor chronic diseases,[4] as well as being able to detect electrochemical biomolecules through Transition Metal Dichalcogenides.[5]

Research

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In 2017, Prasad led a team of bioengineers to create a device that could detect elevated blood-sugar from sweat.[6][7] In 2020, she led a study to develop an assay that could be used to detect and measure the concentration of THC from cannabis in saliva.[8] In 2021, Prasad developed a biosensor, which uses the same technology as the sweat analysis device from 2017, with the addition that the device could detect cortisol.[9]

Prasad's research has included developing a sensor that monitor's patients after suffering a Traumatic Brain Injury by monitoring their sweat. This sensor works by monitoring two specific proteins called GFAP and IL-6.[10] In addition, Prasad's research includes monitoring the neurotransmitter called acetylcholine in the nervous system, which helps monitor many types of brain diseases that could afflict patients.[11]

Entrepreneurship

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In 2014, Shalini Prasad and Sriram Muthukumar co-founded the company EnLiSense LLC, which develops biosensors such as their EnLiSense sensor technology.[12][13] EnLiSense LLC has developed a wearable bracelet-like device that monitors an individual’s alcohol consumption by monitoring their sweat.[14] Ethyl Glucuronide, as well as Ethanol, are substances found in alcohol and are monitored by this device. The wearable device makes direct contact with the skin, and when the user sweats, the device analyses how much alcohol the user has consumed and will send the results to the user's smartphone.[15]

References

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  1. ^ "Shalini Prasad, Ph.D." American Institute for Medical and Biological Engineering. Retrieved April 25, 2022.
  2. ^ "Shalini Prasad - Bioengineering | The University of Texas at Dallas". be.utdallas.edu. Retrieved 2024-03-20.
  3. ^ Prasad, Shalini. "LinkedIn". LinkedIn. Retrieved 2024-03-20.
  4. ^ Upasham, Sayali; Pali, Madhavi; Jagannath, Badrinath; Lin, Kai-Chun; Prasad, Shalini (2023). "Electrochemical Aptasensing for Lifestyle and Chronic Disease Management". Current Medicinal Chemistry. 30 (8): 895–909. doi:10.2174/0929867329666220520111715. ISSN 1875-533X. PMID 35619314.
  5. ^ Madhurantakam, Sasya; Mathew, Georgeena; David, Bianca Elizabeth; Naqvi, Aliya; Prasad, Shalini (2023-11-22). "Recent Progress in Transition Metal Dichalcogenides for Electrochemical Biomolecular Detection". Micromachines. 14 (12): 2139. doi:10.3390/mi14122139. ISSN 2072-666X. PMC 10745343. PMID 38138308.
  6. ^ "CBS News - Researcher: New Wearable Sweat-Sensing Device Measures Blood Sugar". CBS News.
  7. ^ "KERA News - This Coin-Sized Sensor Could Help Detect Risk For Type 2 Diabetes Without Finger Pricking". 12 July 2017.
  8. ^ "Forbes - This Cannabis Saliva Test Could One Day Be Used To Detect Impaired Driving". Forbes.
  9. ^ "IEEE Spectrum - Stress Levels Revealed in Micro-Beads of Sweat".
  10. ^ Shahub, Sarah; Lin, Kai-Chun; Muthukumar, Sriram; Prasad, Shalini (2022-11-30). "A Proof-of-Concept Electrochemical Skin Sensor for Simultaneous Measurement of Glial Fibrillary Acidic Protein (GFAP) and Interleukin-6 (IL-6) for Management of Traumatic Brain Injuries". Biosensors. 12 (12): 1095. doi:10.3390/bios12121095. ISSN 2079-6374. PMC 9775589. PMID 36551062.
  11. ^ Chen, Jie; Lin, Kai-Chun; Prasad, Shalini; Schmidtke, David W. (2023-09-01). "Label free impedance based acetylcholinesterase enzymatic biosensors for the detection of acetylcholine". Biosensors & Bioelectronics. 235 115340. doi:10.1016/j.bios.2023.115340. ISSN 1873-4235. PMID 37216844.
  12. ^ "Tracxn - EnLiSense".
  13. ^ "Texas Monthly - Sepsis Kills Millions Each Year. This UT-Dallas Device Aims to Stop That". 10 February 2021.
  14. ^ "AWARE A Wearable Awareness with Real time Exposure Rapid Wearable Alcohol Diagnostics | SBIR.gov". www.sbir.gov. Retrieved 2024-03-19.
  15. ^ "AWARE A Wearable Awareness with Real time Exposure Rapid Wearable Alcohol Diagnostics | SBIR.gov". www.sbir.gov. Retrieved 2024-03-19.
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