Jonathon Nixon-Abell
Jonathon Nixon-Abell (born 1988) is a British neuroscientist and cell biologist whose research focuses on the organization and dynamics of intracellular organelles, particularly in neurons. He is a group leader and Wellcome Trust Fellow in Clinical Neurosciences at the Cambridge Institute for Medical Research, at the University of Cambridge.[1]
Education and career
[edit]Nixon-Abell received his BSc in Neuroscience from University College London. He completed his PhD in Molecular Neuroscience through a joint programme between University College London and the U.S. National Institutes of Health, where his doctoral research examined endoplasmic reticulum structure and function.[2] He subsequently undertook postdoctoral research at the Howard Hughes Medical Institute's Janelia Research Campus and the University of Cambridge as a Sir Henry Wellcome Fellow, working on advanced imaging approaches to study endoplasmic reticulum dynamics and organelle interactions.[3][4][5] In 2024, Nixon-Abell was awarded a Wellcome Trust Career Development Award, under which he established his independent research group at the University of Cambridge.[6][7]
Research
[edit]Nixon-Abell's research focuses on understanding how intracellular organelles are shaped, trafficked and communicate with one another, and how these processes contribute to cellular homeostasis and disease.[1][8][9][10] Nixon-Abell has also contributed to the Encyclopaedia of Cell Biology, [11] and published an opinion piece in the Financial Times discussing the importance of diversity and interdisciplinary approaches in the development of COVID-19 vaccines.[12]
References
[edit]- ^ a b Nixon-Abell, Jonathon (2021-01-25). "Dr Jonathon Nixon-Abell". www.cimr.cam.ac.uk. Retrieved 2026-03-16.
- ^ Nixon-Abell, Jonathon; Obara, Christopher J.; Weigel, Aubrey V.; Li, Dong; Legant, Wesley R.; Xu, C. Shan; Pasolli, H. Amalia; Harvey, Kirsten; Hess, Harald F.; Betzig, Eric; Blackstone, Craig; Lippincott-Schwartz, Jennifer (2016-10-28). "Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER". Science. 354 (6311) aaf3928. doi:10.1126/science.aaf3928. ISSN 1095-9203. PMC 6528812. PMID 27789813.
- ^ "Biomolecular condensation of hairpin proteins coordinates cytoplasmic clients to spatially distinct microdomains of the ER membrane - Grants Awarded". Wellcome. Retrieved 2026-03-16.
- ^ Obara, Christopher J.; Nixon-Abell, Jonathon; Moore, Andrew S.; Riccio, Federica; Hoffman, David P.; Shtengel, Gleb; Xu, C. Shan; Schaefer, Kathy; Pasolli, H. Amalia; Masson, Jean-Baptiste; Hess, Harald F.; Calderon, Christopher P.; Blackstone, Craig; Lippincott-Schwartz, Jennifer. "Motion of VAPB molecules reveals ER-mitochondria contact site subdomains". Nature. 626 (7997): 169–176. doi:10.1038/s41586-023-06956-y. ISSN 1476-4687. PMC 10830423. PMID 38267577.
- ^ Nixon-Abell, Jonathon; Ruggeri, Francesco S.; Qamar, Seema; Herling, Therese W.; Czekalska, Magdalena A.; Shen, Yi; Wang, Guozhen; King, Christopher; Fernandopulle, Michael S.; Sneideris, Tomas; Watson, Joseph L.; Pillai, Visakh V. S.; Meadows, William; Henderson, James W.; Chambers, Joseph E. (2025-03-21). "ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes". Nature Communications. 16 (1): 2814. doi:10.1038/s41467-025-58142-5. ISSN 2041-1723. PMC 11928461. PMID 40118863.
- ^ "Understanding the role of organelle contact networks in neuronal health and disease - Grants Awarded". Wellcome. Retrieved 2026-03-16.
- ^ Grosse, J. (2023-11-16). "CIMR welcomes two new Principal Investigators". www.cimr.cam.ac.uk. Retrieved 2026-03-16.
- ^ "Jonathon Nixon-Abell". scholar.google.com. Retrieved 2026-03-16.
- ^ "Closer look reveals tubule structure of endoplasmic reticulum". Archived from the original on 2022-11-15. Retrieved 2026-03-16.
- ^ "Scientists need to redraw picture of cell's biggest organelle". 2016-10-27. Retrieved 2026-03-16.
- ^ "The Endoplasmic Reticulum". The Encyclopaedia of Cell Biology: 193–207. 2023-01-01. doi:10.1016/B978-0-12-821618-7.00229-7.
- ^ Nixon-Abell, Jonathon (22 May 2020). "A diverse approach is vital in the hunt for a coronavirus vaccine". www.ft.com. Archived from the original on 2023-03-29. Retrieved 2026-03-17.
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