Angelicin synthase
| Angelicin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.14.148 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Angelicin synthase (EC 1.14.14.148, CYP71AJ4 (gene)) is an enzyme with systematic name (+)-columbianetin,NADPH:oxygen oxidoreductase.[1] It catalyses the following chemical reaction:
-columbianetin.svg)
Angelicin synthase is a cytochrome P450 protein containing heme, isolated from parsnip. It uses molecular oxygen for the oxidation and requires a partner cytochrome P450 reductase for functional expression. This uses nicotinamide adenine dinucleotide phosphate.[2]
References
[edit]- ^ Larbat R, Hehn A, Hans J, Schneider S, Jugdé H, Schneider B, Matern U, Bourgaud F (February 2009). "Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis". The Journal of Biological Chemistry. 284 (8): 4776–85. doi:10.1074/jbc.M807351200. PMID 19098286.
- ^ Enzyme 1.14.14.148 at KEGG Pathway Database.
External links
[edit]- Angelicin+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
