+ reduced
acceptor
Estradiol 6beta-monooxygenase
(Redirected from Estradiol 6b-monooxygenase)
| Estradiol 6-beta-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.99.11 | ||||||||
| CAS no. | 9029-70-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Estradiol 6beta-monooxygenase (EC 1.14.99.11) is an enzyme that catalyzes the chemical reaction:[1]
Estradiol 6β-monooxygenase is an oxidoreductase, that uses molecular oxygen to introduce a hydroxy group at a specific position in the female sex hormone, estradiol. The systematic name of this enzyme class is estradiol-17beta,hydrogen-donor:oxygen oxidoreductase (6beta-hydroxylating). This enzyme is also called estradiol 6beta-hydroxylase.[2][3]
References
[edit]- ^ Enzyme 1.14.99.11 at KEGG Pathway Database.
- ^ Haines WJ (1952). "The biosynthesis of adrenal cortex hormones". Recent Progr. Hormone Res. 7: 255–305.
- ^ Mueller GC, Rumney G (1957). "Formation of 6beta-hydroxy and 6-keto derivatives of estradiol-16-C14 by mouse liver microsomes". J. Am. Chem. Soc. 79 (4): 1004–1005. Bibcode:1957JAChS..79R1004M. doi:10.1021/ja01561a068.
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